But Carboplatin dose didn’t seem to be holding its breath.
Kindness of strangers benefits tallest man. But it was the exact opposite. That wasn’t the sound of Barney and Betty Rubble’s son, but rather the one two punch that Onyx Pharmaceuticals Nasdaq ONXX has received recently. Nexavar caused a higher rate of death in the approximately of patients who had squamous cell cancer, a subtype of NSCLC.
The trial compared Nexavar to placebo with all the patients getting the standard chemotherapeutic agents carboplatin and , both generic versions of drugs from Bristol Myers Squibb NYSE BMY. It looks like the wonder drug isn’t so wonderful after all.
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Since Onyx doesn’t really know how fast Nexavar will be adopted for use in liver cancer or how much Pfizer s NYSE PFE Sutent will cut into sales for kidney cancer patients, Onyx wasn’t willing to give a prediction for sales of Nexavar this year. FDA probing suicide risks from asthma drug. Onyx doesn’t know why Nexavar increased the death rate in patients with squamous cell cancer, but it did say that it wasn’t the same bleeding problem that Avastin has. Fl color promo a img, fl color promo img border noneimportant. The ultimate guide to the best travel Web sites.
A costs for launching as a liver cancer drug.
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Font family Tahoma, Lucida Grande, sans serif. It is possible that the duo could run an additional trial excluding patients with squamous cell cancer to show that Nexavar helps patients with other lung cancers. Chicago battles rise in teen murders. Police free boy,, who was kidnapped as infant. The two most interesting are its multiple phase trials for breast cancer a very large market and a planned trial to test it in combination with surgery for liver cancer. Kin speak of switched identity ordeal.
Of course the duo isn’t going to kill its development of Nexavar for other indications, so the future value of Onyx will ultimately be determined by whether it’s able to expand Nexavar’s label further. Military warns Bush over Iraq strain.
Poor results from the one trick pony the stock to fall over the past two days.
If it can get Nexavar approved for either of those indications, Onyx’s shares will soar again, but if they’re flubs like its lung cancer program, there’s little upside from here.
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Based on the most recent quarter, the run rate for Nexavar sales is about million per year, but that should increase as it launches in more European countries and has full quarters of marketing for liver cancer in the U. CoverSpat li a visited color DEF. Photos Five weeks of mistaken identity. Future Clearly, Monday wasn’t a good day to own Onyx, but with its new, smaller market cap, Onyx is looking a little more . The data monitoring committee stopped the trial because there was no way for the trial to meet its primary endpoint of longer survival of patients with non small cell lung cancer NSCLC.
D costs for clinical trials and SG amp. Container li a hover color FC. Com i msnbc Art SITEWIDE coverSpat test. Fl color promo padding top px. Sales were actually up over the third quarter of, but the increase wasn’t enough to overcome higher R amp.
Let’s take a look at the results and, more importantly, whether Onyx is a better value now that investors have knocked it out of the stratosphere in which it used to orbit. Back to red After one quarter of , expenses sent Onyx back into the red in the fourth quarter of last year. The poor results probably won’t affect sales for liver and kidney cancer patients, but lung cancer is a much larger market, and could have doubled sales of Nexavar. No escape When I saw Monday’s announcement that Onyx and its partner Bayer were stopping their phase clinical trial dubbed ESCAPE Evaluation of Sorafenib, Carboplatin And Paclitaxel Efficacy in NSCLC I figured that Nexavar had met its primary endpoint early, as it’s done multiple times before. .